STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HomKEGG: ssr:SALIVB_0491 7.6e-218 hom; homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 9.97. (428 aa)    
Predicted Functional Partners:
ThrB
Homoserine kinase; KEGG: stf:Ssal_01693 4.0e-141 thrB; homoserine kinase; K00872 homoserine kinase.
 
 0.997
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
  
 0.968
ThrC
Threonine synthase; KEGG: stj:SALIVA_1946 2.8e-252 thrc; threonine synthase (TS); Psort location: Cytoplasmic, score: 9.26.
 
 
 0.955
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
 
 0.947
MetA
KEGG: stj:SALIVA_0867 6.4e-166 metA; homoserine O-acetyltransferase (or homoserine O-succinyltransferase); Psort location: Cytoplasmic, score: 9.97.
  
 
 0.940
MetB1
KEGG: stj:SALIVA_0327 8.3e-189 metB; cystathionine gamma-synthase (CGS) (O-succinylhomoserine (thiol)-lyase); Psort location: Cytoplasmic, score: 9.97.
  
 
 0.902
CysD
O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; KEGG: stn:STND_0945 3.3e-224 O-acetylhomoserine sulfhydrylase, putative; K01740 O-acetylhomoserine (thiol)-lyase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.868
BcaT
Branched-chain-amino-acid transaminase; KEGG: stf:Ssal_01567 2.2e-179 ilvE; branched-chain amino acid aminotransferase; K00826 branched-chain amino acid aminotransferase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.868
LysC
Aspartate kinase; KEGG: stf:Ssal_01811 2.6e-233 lysC; aspartate kinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 8.96; Belongs to the aspartokinase family.
 
 0.848
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.845
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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