STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RuvAKEGG: stj:SALIVA_0068 2.1e-96 ruvA; holliday junction ATP-dependent DNA helicase ruvA; Psort location: Cytoplasmic, score: 9.26. (196 aa)    
Predicted Functional Partners:
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
 
 0.999
RecG
KEGG: ssr:SALIVB_1850 0. recG; ATP-dependent DNA helicase recG K03655; Psort location: Cytoplasmic, score: 9.97.
    
 0.886
pcrA
KEGG: stf:Ssal_01088 0. uvrD; ATP-dependent DNA helicase PcrA; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.861
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity); Belongs to the RecA family.
  
  
 0.842
KXU57824.1
KEGG: stu:STH8232_0075 1.5e-93 3-methyladenine DNA glycosylase; K01246 DNA-3-methyladenine glycosylase I.
  
  
 0.796
recN
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
 
  
 0.774
MutL
KEGG: btk:BT9727_3509 5.6e-151 mutL; DNA mismatch repair protein K03572; Psort location: Cytoplasmic, score: 9.97.
    
 0.746
KXU57825.1
Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.2e-13 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96.
  
    0.737
KXU59027.1
KEGG: stj:SALIVA_1772 0. addA; ATP-dependent nuclease subunit A (ATP-dependent helicase addA); Psort location: Cytoplasmic, score: 9.97.
    
 0.727
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.653
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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