STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXU57783.1KEGG: crn:CAR_c18280 1.0e-62 LacI family transcriptional regulator; Psort location: Cytoplasmic, score: 9.26. (333 aa)    
Predicted Functional Partners:
ptsH
Phosphocarrier protein HPr; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
   
 
 0.714
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 
 0.608
KXU58470.1
UbiC transcription regulator-associated domain protein; KEGG: bcz:BCZK3111 1.2e-24 GntR family transcriptional regulator K00837; Psort location: Cytoplasmic, score: 9.97.
  
   
 0.585
KXU59317.1
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; KEGG: stj:SALIVA_0383 0. fruA; PTS system fructose-specific EIIABC component (EIIABC-Fru); Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.546
PotA1
ABC transporter, ATP-binding protein; KEGG: ssr:SALIVB_1052 2.5e-196 ugpC; sn-glycerol-3-phosphate import ATP-binding protein ugpC K10112; Psort location: CytoplasmicMembrane, score: 7.88.
 
  
 0.543
KXU57782.1
ABC transporter, solute-binding protein; KEGG: snc:HMPREF0837_10106 2.8e-30 maltose/maltodextrin ABC transporter ATP-binding protein K10108; Psort location: Periplasmic, score: 10.00.
  
  
 0.541
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
    
   0.533
KXU58272.1
KEGG: bcz:BCZK3111 2.6e-10 GntR family transcriptional regulator K00837; Psort location: Cytoplasmic, score: 9.26.
  
   
 0.530
KXU57780.1
KEGG: llk:LLKF_1844 4.9e-72 malG; maltose ABC transporter permease K10110; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.500
KXU57781.1
ABC transporter, permease protein; KEGG: ssr:SALIVB_1050 6.3e-230 fructose-bisphosphate aldolase K10109; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.495
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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