STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXU57622.1Stage 0 sporulation protein J domain protein; KEGG: pub:SAR11_0354 4.3e-25 parB; chromosome partitioning protein K03497; Psort location: Cytoplasmic, score: 9.97. (167 aa)    
Predicted Functional Partners:
KXU57190.1
ParB-like protein; KEGG: hhe:HH0423 1.9e-13 parB; transcriptional regulator involved in chromosome partitioning ParB K03497; Psort location: Cytoplasmic, score: 9.26.
 
     0.974
KXU56195.1
Putative stage III sporulation protein E; KEGG: pen:PSEEN2212 8.5e-116 ftsK; cell division protein FtsK K03466; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.737
DnaA
Replication initiator protein DnaA; KEGG: pfe:PSF113_0001 1.5e-73 dnaA; ATPase DnaA K02313; Psort location: Cytoplasmic, score: 9.94.
 
  
 0.736
rsmG
16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
  
  
 0.603
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.545
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
  
 0.533
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.531
KXU59563.1
Segregation and condensation protein B; KEGG: apb:SAR116_0418 1.9e-15 transcriptional regulator containing the HTH domain K06024; Psort location: Cytoplasmic, score: 9.97.
  
   
 0.475
Smc
Segregation protein SMC; KEGG: ssr:SALIVB_0809 0. glucose-6-phosphate 1-dehydrogenase K03529; Psort location: Cytoplasmic, score: 9.94.
 
 
 0.475
DnaN
KEGG: ssr:SALIVB_0002 1.2e-185 dnaN; beta subunit of DNA polymerase III; K02338 DNA polymerase III subunit beta; Psort location: Cytoplasmic, score: 9.26.
     
 0.470
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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