| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DnaA | DnaN | HMPREF3219_0201283 | HMPREF3219_0201284 | Replication initiator protein DnaA; KEGG: pfe:PSF113_0001 1.5e-73 dnaA; ATPase DnaA K02313; Psort location: Cytoplasmic, score: 9.94. | KEGG: ssr:SALIVB_0002 1.2e-185 dnaN; beta subunit of DNA polymerase III; K02338 DNA polymerase III subunit beta; Psort location: Cytoplasmic, score: 9.26. | 0.995 |
| DnaA | KXU56195.1 | HMPREF3219_0201283 | HMPREF3219_0201988 | Replication initiator protein DnaA; KEGG: pfe:PSF113_0001 1.5e-73 dnaA; ATPase DnaA K02313; Psort location: Cytoplasmic, score: 9.94. | Putative stage III sporulation protein E; KEGG: pen:PSEEN2212 8.5e-116 ftsK; cell division protein FtsK K03466; Psort location: CytoplasmicMembrane, score: 10.00. | 0.487 |
| DnaA | KXU57190.1 | HMPREF3219_0201283 | HMPREF3219_0201495 | Replication initiator protein DnaA; KEGG: pfe:PSF113_0001 1.5e-73 dnaA; ATPase DnaA K02313; Psort location: Cytoplasmic, score: 9.94. | ParB-like protein; KEGG: hhe:HH0423 1.9e-13 parB; transcriptional regulator involved in chromosome partitioning ParB K03497; Psort location: Cytoplasmic, score: 9.26. | 0.518 |
| DnaA | KXU57622.1 | HMPREF3219_0201283 | HMPREF3219_0201282 | Replication initiator protein DnaA; KEGG: pfe:PSF113_0001 1.5e-73 dnaA; ATPase DnaA K02313; Psort location: Cytoplasmic, score: 9.94. | Stage 0 sporulation protein J domain protein; KEGG: pub:SAR11_0354 4.3e-25 parB; chromosome partitioning protein K03497; Psort location: Cytoplasmic, score: 9.97. | 0.736 |
| DnaA | ftsZ | HMPREF3219_0201283 | HMPREF3219_0201218 | Replication initiator protein DnaA; KEGG: pfe:PSF113_0001 1.5e-73 dnaA; ATPase DnaA K02313; Psort location: Cytoplasmic, score: 9.94. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.492 |
| DnaA | polA | HMPREF3219_0201283 | HMPREF3219_0200498 | Replication initiator protein DnaA; KEGG: pfe:PSF113_0001 1.5e-73 dnaA; ATPase DnaA K02313; Psort location: Cytoplasmic, score: 9.94. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.552 |
| DnaA | rsmG | HMPREF3219_0201283 | HMPREF3219_0200060 | Replication initiator protein DnaA; KEGG: pfe:PSF113_0001 1.5e-73 dnaA; ATPase DnaA K02313; Psort location: Cytoplasmic, score: 9.94. | 16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | 0.420 |
| DnaN | DnaA | HMPREF3219_0201284 | HMPREF3219_0201283 | KEGG: ssr:SALIVB_0002 1.2e-185 dnaN; beta subunit of DNA polymerase III; K02338 DNA polymerase III subunit beta; Psort location: Cytoplasmic, score: 9.26. | Replication initiator protein DnaA; KEGG: pfe:PSF113_0001 1.5e-73 dnaA; ATPase DnaA K02313; Psort location: Cytoplasmic, score: 9.94. | 0.995 |
| DnaN | KXU57622.1 | HMPREF3219_0201284 | HMPREF3219_0201282 | KEGG: ssr:SALIVB_0002 1.2e-185 dnaN; beta subunit of DNA polymerase III; K02338 DNA polymerase III subunit beta; Psort location: Cytoplasmic, score: 9.26. | Stage 0 sporulation protein J domain protein; KEGG: pub:SAR11_0354 4.3e-25 parB; chromosome partitioning protein K03497; Psort location: Cytoplasmic, score: 9.97. | 0.470 |
| DnaN | ftsZ | HMPREF3219_0201284 | HMPREF3219_0201218 | KEGG: ssr:SALIVB_0002 1.2e-185 dnaN; beta subunit of DNA polymerase III; K02338 DNA polymerase III subunit beta; Psort location: Cytoplasmic, score: 9.26. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.611 |
| DnaN | polA | HMPREF3219_0201284 | HMPREF3219_0200498 | KEGG: ssr:SALIVB_0002 1.2e-185 dnaN; beta subunit of DNA polymerase III; K02338 DNA polymerase III subunit beta; Psort location: Cytoplasmic, score: 9.26. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.999 |
| DnaN | rsmG | HMPREF3219_0201284 | HMPREF3219_0200060 | KEGG: ssr:SALIVB_0002 1.2e-185 dnaN; beta subunit of DNA polymerase III; K02338 DNA polymerase III subunit beta; Psort location: Cytoplasmic, score: 9.26. | 16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | 0.422 |
| DnaN | topA | HMPREF3219_0201284 | HMPREF3219_0200726 | KEGG: ssr:SALIVB_0002 1.2e-185 dnaN; beta subunit of DNA polymerase III; K02338 DNA polymerase III subunit beta; Psort location: Cytoplasmic, score: 9.26. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.715 |
| KXU56195.1 | DnaA | HMPREF3219_0201988 | HMPREF3219_0201283 | Putative stage III sporulation protein E; KEGG: pen:PSEEN2212 8.5e-116 ftsK; cell division protein FtsK K03466; Psort location: CytoplasmicMembrane, score: 10.00. | Replication initiator protein DnaA; KEGG: pfe:PSF113_0001 1.5e-73 dnaA; ATPase DnaA K02313; Psort location: Cytoplasmic, score: 9.94. | 0.487 |
| KXU56195.1 | KXU57190.1 | HMPREF3219_0201988 | HMPREF3219_0201495 | Putative stage III sporulation protein E; KEGG: pen:PSEEN2212 8.5e-116 ftsK; cell division protein FtsK K03466; Psort location: CytoplasmicMembrane, score: 10.00. | ParB-like protein; KEGG: hhe:HH0423 1.9e-13 parB; transcriptional regulator involved in chromosome partitioning ParB K03497; Psort location: Cytoplasmic, score: 9.26. | 0.655 |
| KXU56195.1 | KXU57622.1 | HMPREF3219_0201988 | HMPREF3219_0201282 | Putative stage III sporulation protein E; KEGG: pen:PSEEN2212 8.5e-116 ftsK; cell division protein FtsK K03466; Psort location: CytoplasmicMembrane, score: 10.00. | Stage 0 sporulation protein J domain protein; KEGG: pub:SAR11_0354 4.3e-25 parB; chromosome partitioning protein K03497; Psort location: Cytoplasmic, score: 9.97. | 0.737 |
| KXU56195.1 | ftsZ | HMPREF3219_0201988 | HMPREF3219_0201218 | Putative stage III sporulation protein E; KEGG: pen:PSEEN2212 8.5e-116 ftsK; cell division protein FtsK K03466; Psort location: CytoplasmicMembrane, score: 10.00. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.511 |
| KXU56195.1 | polA | HMPREF3219_0201988 | HMPREF3219_0200498 | Putative stage III sporulation protein E; KEGG: pen:PSEEN2212 8.5e-116 ftsK; cell division protein FtsK K03466; Psort location: CytoplasmicMembrane, score: 10.00. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.707 |
| KXU56195.1 | topA | HMPREF3219_0201988 | HMPREF3219_0200726 | Putative stage III sporulation protein E; KEGG: pen:PSEEN2212 8.5e-116 ftsK; cell division protein FtsK K03466; Psort location: CytoplasmicMembrane, score: 10.00. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.589 |
| KXU57190.1 | DnaA | HMPREF3219_0201495 | HMPREF3219_0201283 | ParB-like protein; KEGG: hhe:HH0423 1.9e-13 parB; transcriptional regulator involved in chromosome partitioning ParB K03497; Psort location: Cytoplasmic, score: 9.26. | Replication initiator protein DnaA; KEGG: pfe:PSF113_0001 1.5e-73 dnaA; ATPase DnaA K02313; Psort location: Cytoplasmic, score: 9.94. | 0.518 |