STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
prsRibose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (321 aa)    
Predicted Functional Partners:
AcoL2
Dihydrolipoyl dehydrogenase; KEGG: stj:SALIVA_1069 3.7e-257 adhD; putative dihydrolipoamide dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
   
 0.978
Tkt
Transketolase; KEGG: ssr:SALIVB_1600 0. tkt; transketolase (TK) K00615; Psort location: Cytoplasmic, score: 9.26.
   
 
 0.937
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 0.928
PgmA
Putative phosphoglucomutase; KEGG: stj:SALIVA_1246 6.8e-297 pgmA; phosphoglucomutase; Psort location: Cytoplasmic, score: 8.96.
  
 0.922
RpiA
KEGG: ssr:SALIVB_0939 3.4e-112 rpiA; ribose-5-phosphate isomerase A K01807; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.919
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
     
 0.907
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.834
AcoB1
Putative TPP-dependent acetoin dehydrogenase complex, E1 component, beta subunit; KEGG: stj:SALIVA_0698 4.5e-181 acoB; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta (Acetoin:DCPIP oxidoreductase-beta) (AO:DCPIP OR) (TPP-dependent acetoin dehydrogenase E1 subunit beta); Psort location: Cytoplasmic, score: 9.97.
   
 0.832
AcoB2
KEGG: stf:Ssal_01137 2.6e-169 pdhB; pyruvate dehydrogenase E1 component subunit beta; K00162 pyruvate dehydrogenase E1 component subunit beta; Psort location: Cytoplasmic, score: 9.97.
   
 0.832
KXU57878.1
KEGG: ssr:SALIVB_1527 7.8e-232 glmU; bifunctional glmU UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase K04042; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.815
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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