STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LacSGlycoside/pentoside/hexuronide transporter; KEGG: stj:SALIVA_1400 0. lacS; lactose permease; Psort location: CytoplasmicMembrane, score: 10.00. (634 aa)    
Predicted Functional Partners:
LacZ
KEGG: stj:SALIVA_1399 0. lacZ; beta-galactosidase (Lactase).
 
  
 0.972
KXU59632.1
KEGG: ssr:SALIVB_0208 0. exp5; PTS system glucose-specific EIICBA component; Psort location: CytoplasmicMembrane, score: 10.00.
 
 
0.960
ScrA2
KEGG: stf:Ssal_00287 0. scrA; PTS system sucrose-specific transporter subunit IIBC; K02808 PTS system, sucrose-specific IIA component; K02809 PTS system, sucrose-specific IIB component K02810; Psort location: CytoplasmicMembrane, score: 10.00.
  
 
0.957
galK
Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
 
  
 0.865
ptsI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.837
GalM
Galactose mutarotase; KEGG: stj:SALIVA_1401 2.0e-185 galM; aldose 1-epimerase.
 
  
 0.825
ptsH
Phosphocarrier protein HPr; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
  
 
 0.767
galT
KEGG: stj:SALIVA_1403 1.3e-268 galT; Galactose-1-phosphate uridylyltransferase (Gal-1-P uridylyltransferase) (UDP-glucose--hexose-1-phosphate uridylyltransferase); Psort location: Cytoplasmic, score: 8.96.
 
  
 0.763
KXU59317.1
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; KEGG: stj:SALIVA_0383 0. fruA; PTS system fructose-specific EIIABC component (EIIABC-Fru); Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.704
GalR
Transcriptional regulator, LacI family; KEGG: amt:Amet_1065 1.9e-31 alanine racemase; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.701
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.