STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXU56939.1LrgB-like protein; KEGG: bqy:MUS_0199 1.9e-24 yxaC; holin-like protein; Psort location: CytoplasmicMembrane, score: 10.00. (172 aa)    
Predicted Functional Partners:
KXU56940.1
LrgA family protein; KEGG: btk:BT9727_3424 1.6e-11 holin-like protein K06518; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.979
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.657
KXU56938.1
HAD hydrolase, family IA, variant 1; KEGG: ssr:SALIVB_0503 3.5e-87 phosphoglycolate phosphatase; Psort location: Cytoplasmic, score: 8.96.
       0.656
EzrA
Septation ring formation regulator EzrA; KEGG: tva:TVAG_387410 4.5e-09 viral A-type inclusion protein; K02331 DNA polymerase phi subunit; Psort location: Cytoplasmic, score: 8.96.
       0.456
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.