STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
serCPhosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (364 aa)    
Predicted Functional Partners:
SerA
KEGG: stf:Ssal_00539 1.2e-201 serA; phosphoglycerate dehydrogenase; K00058 D-3-phosphoglycerate dehydrogenase; Psort location: Cytoplasmic, score: 9.26; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 0.998
serB
KEGG: stj:SALIVA_1566 8.9e-105 serB; putative phosphoserine phosphatase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.959
ThrC
Threonine synthase; KEGG: stj:SALIVA_1946 2.8e-252 thrc; threonine synthase (TS); Psort location: Cytoplasmic, score: 9.26.
   
 0.937
CysM1
Cysteine synthase A; KEGG: ssr:SALIVB_0363 1.1e-156 cysM1; cysteine synthase K01738; Psort location: Cytoplasmic, score: 9.26.
  
 
 0.932
KXU56944.1
KEGG: sds:SDEG_0457 1.4e-58 GNAT family acetyltransferase; Psort location: Cytoplasmic, score: 8.96.
       0.786
mnmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
    
 0.747
KXU56706.1
Prephenate dehydratase; KEGG: stf:Ssal_01508 5.6e-135 pheA2; prephenate dehydratase; K04518 prephenate dehydratase; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.678
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
  
  
 0.651
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.626
KXU56942.1
KEGG: stj:SALIVA_1574 8.6e-68 ogt; putative methylated-DNA--protein-cysteine S-methyltransferase; Psort location: Cytoplasmic, score: 9.26.
       0.613
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.