STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXU56954.1KEGG: stj:SALIVA_1587 1.4e-69 folK; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase (7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase) (HPPK) (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) (PPPK); Psort location: Cytoplasmic, score: 9.97. (163 aa)    
Predicted Functional Partners:
KXU56955.1
Dihydroneopterin aldolase; KEGG: ssr:SALIVB_1631 5.3e-52 folB; dihydroneopterin aldolase (DHNA) K01633; Psort location: Cytoplasmic, score: 8.96.
 
 0.999
KXU56957.1
Dihydropteroate synthase; KEGG: stj:SALIVA_1590 9.7e-131 folP; dihydropteroate synthase (DHPS) (Dihydropteroate pyrophosphorylase); Psort location: Cytoplasmic, score: 9.97.
 
 0.998
FolE
GTP cyclohydrolase I; KEGG: stf:Ssal_00521 3.1e-95 folE; GTP cyclohydrolase I; K01495 GTP cyclohydrolase I; Psort location: Cytoplasmic, score: 9.97.
  
 0.993
KXU58617.1
Aminodeoxychorismate synthase, component I; KEGG: stj:SALIVA_1250 6.3e-262 pabB; para-aminobenzoate synthetase; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.758
murB
UDP-N-acetylmuramate dehydrogenase; Cell wall formation.
  
  
 0.733
PotB
ABC transporter, permease protein; KEGG: nms:NMBM01240355_0614 1.8e-39 putrescine ABC transporter permease PotH K11075; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.628
PotC
Putative spermidine/putrescine ABC transporter, permease protein PotC; KEGG: gwc:GWCH70_0325 1.3e-85 ornithine carbamoyltransferase K11070; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.627
potA
Putative spermidine/putrescine ABC transporter, ATP-binding protein PotA; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
     
 0.624
BirA
biotin--[acetyl-CoA-carboxylase] ligase; KEGG: stj:SALIVA_0965 1.5e-159 birA; bifunctional biotin operon repressor/biotin--[acetyl-CoA-carboxylase] synthetase; Psort location: Cytoplasmic, score: 9.26.
  
  
 0.599
KXU56949.1
KEGG: ebe:B21_01129 1.3e-64 potD; potD, subunit of putrescine/spermidine ABC transporter K11069; Psort location: Periplasmic, score: 9.44.
       0.564
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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