| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Dgk | era | HMPREF3219_0201652 | HMPREF3219_0201653 | KEGG: stw:Y1U_C0595 5.0e-63 Diacylglycerol kinase; K00901 diacylglycerol kinase; Psort location: CytoplasmicMembrane, score: 10.00. | Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.823 |
| Dgk | ybeY | HMPREF3219_0201652 | HMPREF3219_0201651 | KEGG: stw:Y1U_C0595 5.0e-63 Diacylglycerol kinase; K00901 diacylglycerol kinase; Psort location: CytoplasmicMembrane, score: 10.00. | Translation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.937 |
| KXU58487.1 | dnaJ | HMPREF3219_0200733 | HMPREF3219_0201814 | Hypothetical protein; KEGG: mct:MCR_1663 2.3e-10 phage shock protein E K03972. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.614 |
| KXU58487.1 | rplK | HMPREF3219_0200733 | HMPREF3219_0200878 | Hypothetical protein; KEGG: mct:MCR_1663 2.3e-10 phage shock protein E K03972. | Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.775 |
| KXU58487.1 | rplO | HMPREF3219_0200733 | HMPREF3219_0200322 | Hypothetical protein; KEGG: mct:MCR_1663 2.3e-10 phage shock protein E K03972. | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.773 |
| KXU58487.1 | rplQ | HMPREF3219_0200733 | HMPREF3219_0200314 | Hypothetical protein; KEGG: mct:MCR_1663 2.3e-10 phage shock protein E K03972. | Ribosomal protein L17; KEGG: apb:SAR116_2416 1.1e-21 50S ribosomal protein L17 K02879; Psort location: Cytoplasmic, score: 9.97. | 0.787 |
| KXU58487.1 | rpsQ | HMPREF3219_0200733 | HMPREF3219_0200332 | Hypothetical protein; KEGG: mct:MCR_1663 2.3e-10 phage shock protein E K03972. | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.887 |
| KXU58487.1 | sodA | HMPREF3219_0200733 | HMPREF3219_0201801 | Hypothetical protein; KEGG: mct:MCR_1663 2.3e-10 phage shock protein E K03972. | Superoxide dismutase, Mn; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. | 0.936 |
| KXU58487.1 | ybeY | HMPREF3219_0200733 | HMPREF3219_0201651 | Hypothetical protein; KEGG: mct:MCR_1663 2.3e-10 phage shock protein E K03972. | Translation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.942 |
| PhoH | era | HMPREF3219_0200250 | HMPREF3219_0201653 | PhoH-like protein; KEGG: reh:H16_A0527 6.7e-68 phoH; phosphate starvation-inducible protein PhoH, ATPase K06217; Psort location: Cytoplasmic, score: 9.97. | Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.561 |
| PhoH | ybeY | HMPREF3219_0200250 | HMPREF3219_0201651 | PhoH-like protein; KEGG: reh:H16_A0527 6.7e-68 phoH; phosphate starvation-inducible protein PhoH, ATPase K06217; Psort location: Cytoplasmic, score: 9.97. | Translation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.874 |
| dnaJ | KXU58487.1 | HMPREF3219_0201814 | HMPREF3219_0200733 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Hypothetical protein; KEGG: mct:MCR_1663 2.3e-10 phage shock protein E K03972. | 0.614 |
| dnaJ | rplK | HMPREF3219_0201814 | HMPREF3219_0200878 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.943 |
| dnaJ | rplO | HMPREF3219_0201814 | HMPREF3219_0200322 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.946 |
| dnaJ | rplQ | HMPREF3219_0201814 | HMPREF3219_0200314 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Ribosomal protein L17; KEGG: apb:SAR116_2416 1.1e-21 50S ribosomal protein L17 K02879; Psort location: Cytoplasmic, score: 9.97. | 0.960 |
| dnaJ | rpsQ | HMPREF3219_0201814 | HMPREF3219_0200332 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.902 |
| dnaJ | sodA | HMPREF3219_0201814 | HMPREF3219_0201801 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Superoxide dismutase, Mn; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. | 0.932 |
| dnaJ | ybeY | HMPREF3219_0201814 | HMPREF3219_0201651 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Translation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.816 |
| era | Dgk | HMPREF3219_0201653 | HMPREF3219_0201652 | Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | KEGG: stw:Y1U_C0595 5.0e-63 Diacylglycerol kinase; K00901 diacylglycerol kinase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.823 |
| era | PhoH | HMPREF3219_0201653 | HMPREF3219_0200250 | Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | PhoH-like protein; KEGG: reh:H16_A0527 6.7e-68 phoH; phosphate starvation-inducible protein PhoH, ATPase K06217; Psort location: Cytoplasmic, score: 9.97. | 0.561 |