STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXU56681.1Transporter, major facilitator family protein; KEGG: ssr:SALIVB_1450 2.6e-201 coaE; Dephospho-CoA kinase; Psort location: CytoplasmicMembrane, score: 10.00. (407 aa)    
Predicted Functional Partners:
KXU56679.1
DNA-formamidopyrimidine glycosylase; KEGG: ssr:SALIVB_1452 3.3e-130 mutM; formamidopyrimidine-DNA glycosylase K10563; Psort location: Cytoplasmic, score: 9.97.
       0.660
KXU56680.1
dephospho-CoA kinase; KEGG: stu:STH8232_0813 4.3e-89 coaE; dephospho-CoA kinase; K00859 dephospho-CoA kinase; Psort location: Cytoplasmic, score: 9.97.
       0.660
era
Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
       0.562
ybeY
Translation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
       0.528
Dgk
KEGG: stw:Y1U_C0595 5.0e-63 Diacylglycerol kinase; K00901 diacylglycerol kinase; Psort location: CytoplasmicMembrane, score: 10.00.
       0.528
SecG
Preprotein translocase, SecG subunit; Psort location: CytoplasmicMembrane, score: 9.82.
  
    0.528
Rnr
KEGG: stj:SALIVA_0636 0. rnr1; exoribonuclease R; Psort location: Cytoplasmic, score: 9.97.
       0.445
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
       0.424
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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