STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SecGPreprotein translocase, SecG subunit; Psort location: CytoplasmicMembrane, score: 9.82. (78 aa)    
Predicted Functional Partners:
secA
Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.
   
 0.995
SecY2
KEGG: apb:SAR116_2411 2.2e-69 preprotein translocase subunit SecY K03076; Psort location: CytoplasmicMembrane, score: 10.00.
   
 0.986
SecA1
KEGG: pen:PSEEN4477 2.7e-87 secA, azi, div; preprotein translocase subunit SecA K03070; Psort location: Cytoplasmic, score: 9.97.
   
 0.983
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
    
 0.971
rplM
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
   0.893
rplU
Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
 
 0.884
rpmF
Ribosomal protein L32; KEGG: apb:SAR116_0011 1.5e-06 50S ribosomal protein L32 K02911; Belongs to the bacterial ribosomal protein bL32 family.
  
   0.874
KXU56115.1
Accessory Sec system translocase SecY2; KEGG: apb:SAR116_2411 5.9e-23 preprotein translocase subunit SecY K03076; Psort location: CytoplasmicMembrane, score: 10.00.
   
 0.867
KXU58258.1
Membrane protein insertase, YidC/Oxa1 family; Psort location: CytoplasmicMembrane, score: 10.00.
  
 0.863
KXU59578.1
Membrane protein insertase, YidC/Oxa1 family; Psort location: CytoplasmicMembrane, score: 10.00.
 
 0.859
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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