STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccpAKEGG: lsn:LSA_08880 1.1e-90 ccpA; catabolite control protein A K02529; Psort location: Cytoplasmic, score: 9.97. (333 aa)    
Predicted Functional Partners:
ptsH
Phosphocarrier protein HPr; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
   
 
 0.782
CodY
GTP-sensing transcriptional pleiotropic repressor CodY; Psort location: Cytoplasmic, score: 9.97.
    
 
 0.726
KXU58470.1
UbiC transcription regulator-associated domain protein; KEGG: bcz:BCZK3111 1.2e-24 GntR family transcriptional regulator K00837; Psort location: Cytoplasmic, score: 9.97.
  
   
 0.649
hprK
HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as probably the pyrophosphate- dependent phosphorylation of 'Ser-46' in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl- phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon so [...]
      
 0.623
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 
 0.608
KXU56690.1
Hypothetical protein; KEGG: bpb:bpr_I0662 0.0024 ogt; methylated-DNA-protein-cysteine S-methyltransferase Ogt; Psort location: Cytoplasmic, score: 8.96.
       0.599
KXU56687.1
Xaa-Pro dipeptidase; KEGG: ste:STER_0678 5.2e-187 dipeptidase; K01271 Xaa-Pro dipeptidase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.589
KXU56691.1
Putative glycerate kinase; KEGG: ssr:SALIVB_1440 8.9e-176 glxK; glycerate kinase K00865; Psort location: Cytoplasmic, score: 9.26.
       0.580
KXU56688.1
Hypothetical protein.
       0.562
KXU56956.1
KEGG: stl:stu1542 5.7e-261 amyL; cytoplasmic alpha-amylase K01176; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.558
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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