STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (427 aa)    
Predicted Functional Partners:
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
 0.997
AroK
Shikimate kinase; KEGG: stj:SALIVA_0657 9.1e-80 aroK; shikimate kinase; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.996
TyrA
KEGG: stf:Ssal_01513 2.0e-187 tyrA2; prephenate dehydrogenase; K04517 prephenate dehydrogenase; Psort location: Cytoplasmic, score: 8.96.
  
 0.990
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
  
 0.988
KXU56698.1
KEGG: ssr:SALIVB_1429 8.0e-136 aroE; shikimate dehydrogenase K00014; Psort location: Cytoplasmic, score: 9.26.
  
 0.985
cmk
Cytidylate kinase; KEGG: stj:SALIVA_1013 5.0e-111 cmk; cytidylate kinase (CK) (Cytidine monophosphate kinase) (CMP kinase); Psort location: Cytoplasmic, score: 9.97.
 
  
 0.925
KXU56706.1
Prephenate dehydratase; KEGG: stf:Ssal_01508 5.6e-135 pheA2; prephenate dehydratase; K04518 prephenate dehydratase; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.883
KXU56707.1
Cell envelope-like function transcriptional attenuator common domain protein; Psort location: CytoplasmicMembrane, score: 9.82.
 
     0.807
DapD1
KEGG: stj:SALIVA_1451 5.6e-96 maa; maltose O-acetyltransferase (Maltose transacetylase); Psort location: Cytoplasmic, score: 9.26.
  
  
 0.655
serC
Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
  
  
 0.651
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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