STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AcoL1KEGG: stj:SALIVA_0696 9.9e-225 lpdA; dihydrolipoyl dehydrogenase (dihydrolipoamide dehydrogenase) (E3 component of 2-oxoglutarate dehydrogenase complex); Psort location: Cytoplasmic, score: 9.97. (446 aa)    
Predicted Functional Partners:
AcoC1
KEGG: stj:SALIVA_0699 1.6e-210 acoC; dihydrolipoyllysine-residue acetyltransferase component of acetoin cleaving system; Psort location: Cytoplasmic, score: 9.97.
 0.997
AcoL2
Dihydrolipoyl dehydrogenase; KEGG: stj:SALIVA_1069 3.7e-257 adhD; putative dihydrolipoamide dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
 
0.986
AcoB2
KEGG: stf:Ssal_01137 2.6e-169 pdhB; pyruvate dehydrogenase E1 component subunit beta; K00162 pyruvate dehydrogenase E1 component subunit beta; Psort location: Cytoplasmic, score: 9.97.
 
 0.984
AcoA2
KEGG: stj:SALIVA_1066 7.9e-168 acetoin dehydrogenase complex, E1 component,alpha subunit; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.969
KXU57756.1
Branched-chain alpha-keto acid dehydrogenase subunit E2; KEGG: stu:STH8232_1236 1.2e-185 acoC; acetoin/pyruvate dehydrogenase complex, E2 component, dihydrolipoamide succinyltransferase; K00627 pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); Psort location: Cytoplasmic, score: 9.97.
 0.953
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.938
AcoB1
Putative TPP-dependent acetoin dehydrogenase complex, E1 component, beta subunit; KEGG: stj:SALIVA_0698 4.5e-181 acoB; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta (Acetoin:DCPIP oxidoreductase-beta) (AO:DCPIP OR) (TPP-dependent acetoin dehydrogenase E1 subunit beta); Psort location: Cytoplasmic, score: 9.97.
 
 0.936
pflB
KEGG: ssr:SALIVB_1775 0. pfl; formate acetyltransferase K00656; Psort location: Cytoplasmic, score: 9.94.
     
 0.905
AcoA1
TPP-dependent acetoin dehydrogenase complex, E1 component, alpha subunit; KEGG: stj:SALIVA_0697 8.6e-194 acoA; acetoin:2,6-dichlorophenolindophenol oxidoreductase alpha subunit (acetoin:DCPIP oxidoreductase-alpha) (AO:DCPIP OR); Psort location: Cytoplasmic, score: 9.97.
 
 
 0.861
LplA
KEGG: ssr:SALIVB_1043 1.3e-172 lplA; putative lipoate-protein ligase A K03800; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.849
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.