STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HsdM1KEGG: stl:stu0711 1.7e-282 hsdM1; type I restriction-modification system methyltransferase subunit; K03427 type I restriction enzyme M protein; Psort location: Cytoplasmic, score: 8.96. (534 aa)    
Predicted Functional Partners:
HsdR1
Putative ATP synthase F1, delta subunit; KEGG: ste:STER_0747 0. type I restriction-modification system restriction subunit; K01153 type I restriction enzyme, R subunit.
 
 
 0.997
KXU56486.1
Hypothetical protein; KEGG: sgo:SGO_0557 5.9e-124 HsdS specificity protein of type I restriction-modification system K01154.
 
 0.997
HsdS2
Hypothetical protein; KEGG: gth:Geoth_2024 3.5e-14 N-6 DNA methylase; K03427 type I restriction enzyme M protein; Psort location: Cytoplasmic, score: 8.96.
 
 0.955
KXU56487.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
       0.764
KXU56484.1
Hypothetical protein; KEGG: efc:EFAU004_01855 1.3e-05 phosphoesterase; Psort location: Cytoplasmic, score: 8.96.
  
    0.737
KXU56485.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
       0.736
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
   
 0.716
KXU56489.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
       0.560
Fbp
Fibronectin-binding domain protein; KEGG: edi:EDI_341030 0.0081 intracellular protein transport protein USO1; Psort location: Cytoplasmic, score: 8.96.
  
    0.523
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.516
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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