STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PpcKEGG: stj:SALIVA_0772 0. ppc; phosphoenolpyruvate carboxylase (PEPCase) (PEPC); Psort location: Cytoplasmic, score: 8.96. (940 aa)    
Predicted Functional Partners:
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.931
pyk
Pyruvate kinase; KEGG: stj:SALIVA_0892 2.2e-250 pyk; pyruvate kinase; Psort location: Cytoplasmic, score: 9.97.
     
 0.928
KXU56460.1
KEGG: stf:Ssal_01390 5.7e-158 holA; DNA polymerase III subunit delta; K02340 DNA polymerase III subunit delta; Psort location: Cytoplasmic, score: 8.96.
       0.785
sodA
Superoxide dismutase, Mn; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
     
 0.574
KXU56458.1
Hypothetical protein.
       0.526
tpiA
Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
  
 0.521
KXU56457.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00.
       0.495
KXU56462.1
Hypothetical protein; KEGG: cci:CC1G_12482 9.9e-11 exopolyphosphatase; K01514 exopolyphosphatase.
 
     0.486
KXU58617.1
Aminodeoxychorismate synthase, component I; KEGG: stj:SALIVA_1250 6.3e-262 pabB; para-aminobenzoate synthetase; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.478
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
  
 0.445
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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