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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXU56428.1Serine-type D-Ala-D-Ala carboxypeptidase; KEGG: stj:SALIVA_0129 6.7e-123 putative D,D-carboxypeptidase (D-alanyl-D-alanine carboxypeptidase); Psort location: Cytoplasmic, score: 9.26. (265 aa)    
Predicted Functional Partners:
KXU56429.1
Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; KEGG: stc:str0117 3.4e-89 mur3; peptidoglycan hydrolase; K01446 N-acetylmuramoyl-L-alanine amidase.
       0.800
KXU56427.1
Hypothetical protein; KEGG: ssr:SALIVB_0144 5.4e-27 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K15634.
  
    0.790
HrcA
Transcription repressor HrcA; KEGG: apb:SAR116_1619 3.5e-11 transcriptional regulator of heat shock gene K03705; Psort location: Cytoplasmic, score: 8.96.
       0.519
grpE
Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]
       0.475
Ddl
KEGG: ssr:SALIVB_1682 7.2e-174 ddl; D-alanine--D-alanine ligase K01921; Psort location: Cytoplasmic, score: 9.97.
 
   
 0.408
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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