Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KXU56207.1KEGG: stc:str1413 0. bifunctional glutamate--cysteine ligase/glutathione synthetase K01919; Psort location: Cytoplasmic, score: 9.97. (758 aa)    
Predicted Functional Partners:
CysM1
Cysteine synthase A; KEGG: ssr:SALIVB_0363 1.1e-156 cysM1; cysteine synthase K01738; Psort location: Cytoplasmic, score: 9.26.
    
 0.970
glnA
KEGG: ssr:SALIVB_1911 7.9e-239 glnA; glutamine synthetase K01915; Psort location: Cytoplasmic, score: 9.97.
    
 0.965
GdhA
KEGG: stj:SALIVA_0404 1.0e-236 gdhA; NADP-specific glutamate dehydrogenase (NADP-GDH).
    
 0.962
KXU57789.1
Membrane alanyl aminopeptidase; KEGG: stj:SALIVA_1090 0. pepN; aminopeptidase N (Lysyl aminopeptidase) (Lys-AP) (Alanine aminopeptidase); Psort location: Cytoplasmic, score: 9.26.
   
 
 0.947
BcaT
Branched-chain-amino-acid transaminase; KEGG: stf:Ssal_01567 2.2e-179 ilvE; branched-chain amino acid aminotransferase; K00826 branched-chain amino acid aminotransferase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.945
KXU59492.1
KEGG: ssr:SALIVB_0350 1.4e-207 patB; putative aminotransferase B K14155; Psort location: Cytoplasmic, score: 9.97.
     
  0.941
pepT
Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
    
 0.830
KXU58275.1
KEGG: stj:SALIVA_1949 0. adhE; aldehyde-alcohol dehydrogenase 2; Psort location: Cytoplasmic, score: 9.97.
    
 0.815
MetB1
KEGG: stj:SALIVA_0327 8.3e-189 metB; cystathionine gamma-synthase (CGS) (O-succinylhomoserine (thiol)-lyase); Psort location: Cytoplasmic, score: 9.97.
    
 0.805
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.746
Your Current Organism:
Streptococcus salivarius
NCBI taxonomy Id: 1304
Other names: ATCC 7073, CCUG 11878, CCUG 17825, CCUG 50207, CIP 102503, DSM 20560, JCM 5707, LMG 11489, LMG:11489, NCIMB 701779, NCTC 8618, S. salivarius, Streptococcus salivarius subsp. salivarius, Streptococcus sp. FStet12, Streptococcus sp. HSISS4
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