STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadKNAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (272 aa)    
Predicted Functional Partners:
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
 
  
 0.915
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.879
EOD00905.1
NAD-dependent protein deacetylase of SIR2 family.
  
 
 0.867
EOC99609.1
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
  
 0.856
EOC99806.1
Hydrolase (HAD superfamily), YqeK.
     
 0.789
EOD00308.1
Dihydrolipoamide dehydrogenase.
   
 0.710
EOC99611.1
RNA binding methyltransferase, FtsJ.
  
  
 0.703
EOD01806.1
Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
  
  
 0.702
cinA
Protein Implicated in DNA repair function with RecA and MutS; Belongs to the CinA family.
  
 
  0.678
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.666
Your Current Organism:
Caldisalinibacter kiritimatiensis
NCBI taxonomy Id: 1304284
Other names: C. kiritimatiensis, Caldisalinibacter kiritimatiensis Ben Hania et al. 2015, Clostridiaceae bacterium L21-TH-D2, DSM 26826, JCM 18664, strain L21-TH-D2
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