STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EOD00500.1Hypothetical protein. (496 aa)    
Predicted Functional Partners:
EOD00501.1
Hypothetical protein.
     0.994
EOD00505.1
HNH endonuclease:HNH nuclease.
   
 
 0.671
EOD00193.1
HNH endonuclease family protein.
   
 
 0.671
EOC99359.1
Hypothetical protein.
   
 
 0.671
EOD01217.1
Ferredoxin reductase.
    
   0.495
EOD00823.1
UPF0028 protein YchK.
    
   0.495
EOC99472.1
Hypothetical protein.
    
   0.495
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.494
EOC99750.1
Hypothetical protein.
 
     0.439
EOC99961.1
Hypothetical protein.
  
     0.424
Your Current Organism:
Caldisalinibacter kiritimatiensis
NCBI taxonomy Id: 1304284
Other names: C. kiritimatiensis, Caldisalinibacter kiritimatiensis Ben Hania et al. 2015, Clostridiaceae bacterium L21-TH-D2, DSM 26826, JCM 18664, strain L21-TH-D2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.