EOD00479.1 protein (Caldisalinibacter kiritimatiensis)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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Score

EOD00479.1

Oligopeptide transport ATP-binding protein OppD; Belongs to the ABC transporter superfamily. (342 aa)

Predicted Functional Partners:

EOD00480.1

0.998

EOD00415.1

0.993

EOD00982.1

0.992

EOD00481.1

0.982

EOD00476.1

0.966

EOD00981.1

0.944

EOD00478.1

0.936

EOD00416.1

0.931

EOD00069.1

0.902

EOD00681.1

0.888

Your Current Organism:

Caldisalinibacter kiritimatiensis

NCBI taxonomy Id: 1304284
Other names: C. kiritimatiensis, Caldisalinibacter kiritimatiensis Ben Hania et al. 2015, Clostridiaceae bacterium L21-TH-D2, DSM 26826, JCM 18664, strain L21-TH-D2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EOD00069.1	EOD00479.1	L21TH_1879	L21TH_1480	ABC transporter related protein.	Oligopeptide transport ATP-binding protein OppD; Belongs to the ABC transporter superfamily.	0.902
EOD00415.1	EOD00416.1	L21TH_1525	L21TH_1526	Oligopeptide transport system permease protein OppC.	Oligopeptide transport system permease protein OppB.	0.991
EOD00415.1	EOD00476.1	L21TH_1525	L21TH_1477	Oligopeptide transport system permease protein OppC.	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA.	0.964
EOD00415.1	EOD00478.1	L21TH_1525	L21TH_1479	Oligopeptide transport system permease protein OppC.	Oligopeptide transport ATP-binding protein OppF.	0.990
EOD00415.1	EOD00479.1	L21TH_1525	L21TH_1480	Oligopeptide transport system permease protein OppC.	Oligopeptide transport ATP-binding protein OppD; Belongs to the ABC transporter superfamily.	0.993
EOD00415.1	EOD00481.1	L21TH_1525	L21TH_1482	Oligopeptide transport system permease protein OppC.	Oligopeptide transport system permease protein OppB.	0.972
EOD00415.1	EOD00981.1	L21TH_1525	L21TH_0949	Oligopeptide transport system permease protein OppC.	Dipeptide transport system permease protein DppB.	0.973
EOD00416.1	EOD00415.1	L21TH_1526	L21TH_1525	Oligopeptide transport system permease protein OppB.	Oligopeptide transport system permease protein OppC.	0.991
EOD00416.1	EOD00476.1	L21TH_1526	L21TH_1477	Oligopeptide transport system permease protein OppB.	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA.	0.946
EOD00416.1	EOD00478.1	L21TH_1526	L21TH_1479	Oligopeptide transport system permease protein OppB.	Oligopeptide transport ATP-binding protein OppF.	0.907
EOD00416.1	EOD00479.1	L21TH_1526	L21TH_1480	Oligopeptide transport system permease protein OppB.	Oligopeptide transport ATP-binding protein OppD; Belongs to the ABC transporter superfamily.	0.931
EOD00416.1	EOD00480.1	L21TH_1526	L21TH_1481	Oligopeptide transport system permease protein OppB.	Oligopeptide transport system permease protein OppC.	0.964
EOD00416.1	EOD00982.1	L21TH_1526	L21TH_0950	Oligopeptide transport system permease protein OppB.	Dipeptide transport system permease protein DppC.	0.962
EOD00476.1	EOD00415.1	L21TH_1477	L21TH_1525	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA.	Oligopeptide transport system permease protein OppC.	0.964
EOD00476.1	EOD00416.1	L21TH_1477	L21TH_1526	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA.	Oligopeptide transport system permease protein OppB.	0.946
EOD00476.1	EOD00478.1	L21TH_1477	L21TH_1479	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA.	Oligopeptide transport ATP-binding protein OppF.	0.966
EOD00476.1	EOD00479.1	L21TH_1477	L21TH_1480	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA.	Oligopeptide transport ATP-binding protein OppD; Belongs to the ABC transporter superfamily.	0.966
EOD00476.1	EOD00480.1	L21TH_1477	L21TH_1481	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA.	Oligopeptide transport system permease protein OppC.	0.977
EOD00476.1	EOD00481.1	L21TH_1477	L21TH_1482	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA.	Oligopeptide transport system permease protein OppB.	0.974
EOD00476.1	EOD00981.1	L21TH_1477	L21TH_0949	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA.	Dipeptide transport system permease protein DppB.	0.933

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Network Stats

number of nodes:

11

number of edges:

54

average node degree:

9.82

avg. local clustering coefficient:

0.982

expected number of edges:

11

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0033611

Oxalate catabolic process

2 of 2

2.74

0.91

0.0225

GO:0022900

Electron transport chain

3 of 51

1.51

0.76

0.0263

GO:0006091

Generation of precursor metabolites and energy

4 of 98

1.35

0.74

0.0225

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016903

Oxidoreductase activity, acting on the aldehyde or oxo group of donors

3 of 15

2.04

1.5

0.0012

GO:0016491

Oxidoreductase activity

8 of 270

1.21

1.49

1.76e-06

GO:0051539

4 iron, 4 sulfur cluster binding

4 of 60

1.57

1.29

0.0012

GO:0030976

Thiamine pyrophosphate binding

2 of 11

2.0

0.84

0.0264

GO:0050136

NADH dehydrogenase (quinone) activity

2 of 18

1.79

0.69

0.0480

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1012

Mixed, incl. Generation of precursor metabolites and energy, and Valine, leucine and isoleucine biosynthesis

11 of 99

1.79

4.85

5.66e-17

CL:1017

Mixed, incl. 4Fe-4S binding domain, and 4Fe-4S dicluster domain

6 of 25

2.12

4.17

6.57e-10

CL:1015

Mixed, incl. Electron transport chain, and Cell redox homeostasis

7 of 42

1.96

4.13

8.96e-11

CL:1023

NADH dehydrogenase (ubiquinone) activity, and 4Fe-4S dicluster domain

5 of 14

2.29

3.95

9.60e-09

CL:1140

Oxalate catabolic process, and Thiamin diphosphate-binding fold

4 of 5

2.64

3.77

7.68e-08

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00020

Citrate cycle (TCA cycle)

7 of 18

2.33

5.86

3.02e-13

map00650

Butanoate metabolism

7 of 24

2.21

5.41

8.24e-13

map00620

Pyruvate metabolism

6 of 45

1.87

3.39

4.48e-09

map01200

Carbon metabolism

7 of 119

1.51

2.45

1.25e-08

map00010

Glycolysis / Gluconeogenesis

5 of 54

1.71

2.45

7.47e-07

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:1990204

Oxidoreductase complex

3 of 40

1.62

0.9

0.0141

GOCC:0045272

Plasma membrane respiratory chain complex I

2 of 10

2.04

0.84

0.0262

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0670

Pyruvate

5 of 18

2.18

3.56

4.21e-08

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF17147

Pyruvate:ferredoxin oxidoreductase core domain II

2 of 3

2.57

0.92

0.0211

PF01855

Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg

2 of 3

2.57

0.92

0.0211

PF01558

Pyruvate ferredoxin/flavodoxin oxidoreductase

2 of 3

2.57

0.92

0.0211

PF01266

FAD dependent oxidoreductase

2 of 4

2.44

0.92

0.0211

PF12838

4Fe-4S dicluster domain

2 of 8

2.14

0.9

0.0211

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00928

NADH-ubiquinone oxidoreductase-F iron-sulfur binding region

2 of 3

2.57

1.29

0.0043

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