STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EOC99617.1Glycine/sarcosine/betaine reductase component C chain 2. (394 aa)    
Predicted Functional Partners:
EOC99618.1
Glycine/sarcosine/betaine reductase component C chain 1.
  
 0.999
EOC99619.1
Glycine reductase component B gamma subunit; Selenocysteine-containing.
 
   
 0.956
grdA
Glycine/sarcosine/betaine reductase protein A; In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine. By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state. Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination.
 
   
 0.928
EOC99621.1
Glycine reductase component B beta subunit / Glycine reductase component B alpha subunit.
 
   
 0.898
EOC99625.1
GrdX protein.
 
   
 0.896
EOD00560.1
Malonyl CoA-acyl carrier protein transacylase.
  
  
 0.842
EOC99623.1
Thioredoxin; Belongs to the thioredoxin family.
 
     0.813
rpmF
LSU ribosomal protein L32p; Belongs to the bacterial ribosomal protein bL32 family.
  
  
 0.786
rpsM
SSU ribosomal protein S13p (S18e); Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.
   
    0.781
rpsH
SSU ribosomal protein S8p (S15Ae); One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
   
    0.763
Your Current Organism:
Caldisalinibacter kiritimatiensis
NCBI taxonomy Id: 1304284
Other names: C. kiritimatiensis, Caldisalinibacter kiritimatiensis Ben Hania et al. 2015, Clostridiaceae bacterium L21-TH-D2, DSM 26826, JCM 18664, strain L21-TH-D2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.