STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa)    
Predicted Functional Partners:
udk
Uridine kinase.
 
 0.996
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.981
EOD01609.1
Uridine kinase.
  
 0.978
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
 
 0.965
pyrF
Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
 
 0.954
EOD01759.1
Ribose 5-phosphate isomerase B.
 
  
 0.940
EOC99862.1
Pyrimidine-nucleoside phosphorylase.
  
 
 0.924
EOD01381.1
Serine hydroxymethyltransferase.
  
  
 0.894
pyrR
Uracil phosphoribosyltransferase/ Pyrimidine operon regulatory protein PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
     
 0.868
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
    
 0.855
Your Current Organism:
Caldisalinibacter kiritimatiensis
NCBI taxonomy Id: 1304284
Other names: C. kiritimatiensis, Caldisalinibacter kiritimatiensis Ben Hania et al. 2015, Clostridiaceae bacterium L21-TH-D2, DSM 26826, JCM 18664, strain L21-TH-D2
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