node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SMF08748.1 | SMF20206.1 | SAMN02745866_00643 | SAMN02745866_01257 | Uncharacterized conserved protein. | Oxidoreductase alpha (molybdopterin) subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.745 |
SMF08748.1 | SMF20263.1 | SAMN02745866_00643 | SAMN02745866_01261 | Uncharacterized conserved protein. | PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein. | 0.689 |
SMF08748.1 | SMF31282.1 | SAMN02745866_00643 | SAMN02745866_02057 | Uncharacterized conserved protein. | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | 0.673 |
SMF08748.1 | SMF45478.1 | SAMN02745866_00643 | SAMN02745866_02952 | Uncharacterized conserved protein. | Uncharacterized conserved protein, DUF2126 family. | 0.699 |
SMF08748.1 | SMF51234.1 | SAMN02745866_00643 | SAMN02745866_03236 | Uncharacterized conserved protein. | Ubiquinol-cytochrome c reductase cytochrome b subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | 0.731 |
SMF08748.1 | guaA | SAMN02745866_00643 | SAMN02745866_03751 | Uncharacterized conserved protein. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.801 |
SMF08748.1 | guaB | SAMN02745866_00643 | SAMN02745866_03752 | Uncharacterized conserved protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.778 |
SMF08748.1 | msrP | SAMN02745866_00643 | SAMN02745866_03302 | Uncharacterized conserved protein. | Sulfoxide reductase catalytic subunit YedY; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to re [...] | 0.699 |
SMF08748.1 | nadE | SAMN02745866_00643 | SAMN02745866_02732 | Uncharacterized conserved protein. | NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.699 |
SMF08748.1 | panC | SAMN02745866_00643 | SAMN02745866_03804 | Uncharacterized conserved protein. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.814 |
SMF20206.1 | SMF08748.1 | SAMN02745866_01257 | SAMN02745866_00643 | Oxidoreductase alpha (molybdopterin) subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Uncharacterized conserved protein. | 0.745 |
SMF20206.1 | SMF51234.1 | SAMN02745866_01257 | SAMN02745866_03236 | Oxidoreductase alpha (molybdopterin) subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Ubiquinol-cytochrome c reductase cytochrome b subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | 0.722 |
SMF20206.1 | guaA | SAMN02745866_01257 | SAMN02745866_03751 | Oxidoreductase alpha (molybdopterin) subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.749 |
SMF20206.1 | msrP | SAMN02745866_01257 | SAMN02745866_03302 | Oxidoreductase alpha (molybdopterin) subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Sulfoxide reductase catalytic subunit YedY; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to re [...] | 0.501 |
SMF20263.1 | SMF08748.1 | SAMN02745866_01261 | SAMN02745866_00643 | PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein. | Uncharacterized conserved protein. | 0.689 |
SMF20263.1 | SMF31282.1 | SAMN02745866_01261 | SAMN02745866_02057 | PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein. | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | 0.514 |
SMF20263.1 | guaA | SAMN02745866_01261 | SAMN02745866_03751 | PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.989 |
SMF20263.1 | guaB | SAMN02745866_01261 | SAMN02745866_03752 | PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.970 |
SMF20263.1 | nadE | SAMN02745866_01261 | SAMN02745866_02732 | PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein. | NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.629 |
SMF31282.1 | SMF08748.1 | SAMN02745866_02057 | SAMN02745866_00643 | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Uncharacterized conserved protein. | 0.673 |