STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A109FIM7Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (814 aa)    
Predicted Functional Partners:
A0A109FIR6
Uncharacterized protein.
  
 0.995
A0A109FML0
Uncharacterized protein.
  
 0.995
A0A109FI58
Deoxythymidylate kinase.
  
 
 0.957
A0A109FDZ7
DNA helicase; Belongs to the MCM family.
   
 
 0.934
A0A109FD08
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 
 0.932
A0A109FJM2
Thymidylate synthase.
  
  
 0.930
A0A120E612
Nucleoside diphosphate kinase.
     
 0.929
A0A125PHP4
DNA helicase; Belongs to the MCM family.
   
 
 0.928
A0A125PJ17
Guanylate kinase.
     
 0.919
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 
 0.916
Your Current Organism:
Rhodotorula sp. JG1b
NCBI taxonomy Id: 1305733
Other names: R. sp. JG-1b, Rhodotorula sp. JG-1b
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.