| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AHC13456.1 | AHC13458.1 | L21SP2_0010 | L21SP2_0012 | Aminomethyltransferase, glycine cleavage system T protein. | Glycine dehydrogenase [decarboxylating], glycine cleavage system P1 protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.999 |
| AHC13456.1 | AHC13459.1 | L21SP2_0010 | L21SP2_0013 | Aminomethyltransferase, glycine cleavage system T protein. | Glycine dehydrogenase [decarboxylating], glycine cleavage system P2 protein. | 0.999 |
| AHC13456.1 | AHC13853.1 | L21SP2_0010 | L21SP2_0421 | Aminomethyltransferase, glycine cleavage system T protein. | 2-amino-3-ketobutyrate coenzyme A ligase. | 0.515 |
| AHC13456.1 | AHC15539.1 | L21SP2_0010 | L21SP2_2176 | Aminomethyltransferase, glycine cleavage system T protein. | Dihydrolipoamide dehydrogenase. | 0.955 |
| AHC13456.1 | AHC16537.1 | L21SP2_0010 | L21SP2_3197 | Aminomethyltransferase, glycine cleavage system T protein. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.935 |
| AHC13456.1 | folD | L21SP2_0010 | L21SP2_1854 | Aminomethyltransferase, glycine cleavage system T protein. | Methylenetetrahydrofolate dehydrogenase (NADP+)/ Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.967 |
| AHC13456.1 | gcvH | L21SP2_0010 | L21SP2_0011 | Aminomethyltransferase, glycine cleavage system T protein. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
| AHC13456.1 | glyA | L21SP2_0010 | L21SP2_0784 | Aminomethyltransferase, glycine cleavage system T protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.997 |
| AHC13456.1 | kbl | L21SP2_0010 | L21SP2_1334 | Aminomethyltransferase, glycine cleavage system T protein. | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.515 |
| AHC13458.1 | AHC13456.1 | L21SP2_0012 | L21SP2_0010 | Glycine dehydrogenase [decarboxylating], glycine cleavage system P1 protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Aminomethyltransferase, glycine cleavage system T protein. | 0.999 |
| AHC13458.1 | AHC13459.1 | L21SP2_0012 | L21SP2_0013 | Glycine dehydrogenase [decarboxylating], glycine cleavage system P1 protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Glycine dehydrogenase [decarboxylating], glycine cleavage system P2 protein. | 0.999 |
| AHC13458.1 | AHC13853.1 | L21SP2_0012 | L21SP2_0421 | Glycine dehydrogenase [decarboxylating], glycine cleavage system P1 protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 2-amino-3-ketobutyrate coenzyme A ligase. | 0.918 |
| AHC13458.1 | AHC15539.1 | L21SP2_0012 | L21SP2_2176 | Glycine dehydrogenase [decarboxylating], glycine cleavage system P1 protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Dihydrolipoamide dehydrogenase. | 0.927 |
| AHC13458.1 | AHC16319.1 | L21SP2_0012 | L21SP2_2973 | Glycine dehydrogenase [decarboxylating], glycine cleavage system P1 protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Low-specificity L-threonine aldolase. | 0.923 |
| AHC13458.1 | AHC16537.1 | L21SP2_0012 | L21SP2_3197 | Glycine dehydrogenase [decarboxylating], glycine cleavage system P1 protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.926 |
| AHC13458.1 | folD | L21SP2_0012 | L21SP2_1854 | Glycine dehydrogenase [decarboxylating], glycine cleavage system P1 protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Methylenetetrahydrofolate dehydrogenase (NADP+)/ Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.930 |
| AHC13458.1 | gcvH | L21SP2_0012 | L21SP2_0011 | Glycine dehydrogenase [decarboxylating], glycine cleavage system P1 protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
| AHC13458.1 | glyA | L21SP2_0012 | L21SP2_0784 | Glycine dehydrogenase [decarboxylating], glycine cleavage system P1 protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.975 |
| AHC13458.1 | kbl | L21SP2_0012 | L21SP2_1334 | Glycine dehydrogenase [decarboxylating], glycine cleavage system P1 protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.918 |
| AHC13459.1 | AHC13456.1 | L21SP2_0013 | L21SP2_0010 | Glycine dehydrogenase [decarboxylating], glycine cleavage system P2 protein. | Aminomethyltransferase, glycine cleavage system T protein. | 0.999 |
