Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AHC13867.1Adenylate cyclase. (553 aa)    
Predicted Functional Partners:
AHC15573.1
GTP pyrophosphokinase, (p)ppGpp synthetase I; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
    
 0.911
AHC16320.1
RelA/SpoT domain protein.
   
 0.908
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.904
AHC16659.1
Ribonucleotide reductase of class III (anaerobic), large subunit.
    
  0.904
AHC13744.1
cAMP-binding protein.
 
 
 0.829
AHC15293.1
Cyclic nucleotide-binding protein.
 
 
 0.813
AHC15107.1
Cyclic nucleotide binding domain protein.
 
 
 0.805
ribA
3,4-dihydroxy-2-butanone 4-phosphate synthase/ GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.
     
  0.800
AHC14813.1
Transcriptional regulator, Crp/Fnr family.
 
 
 0.800
folE2
GTP cyclohydrolase Itype 2; Converts GTP to 7,8-dihydroneopterin triphosphate.
     
  0.800
Your Current Organism:
Salinispira pacifica
NCBI taxonomy Id: 1307761
Other names: DSM 27196, JCM 18663, S. pacifica, Salinispira pacifica Ben Hania et al. 2015, Spirochaeta sp. L21-RPul-D2, strain L21-RPul-D2
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