Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nnrDNAD(P)HX epimerase / NAD(P)HX dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. (624 aa)    
Predicted Functional Partners:
AHC15748.1
Adenosylhomocysteinase.
  
 0.931
groL
Heat shock protein 60 family chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 
 0.827
AHC14617.1
Lipoprotein, putative.
       0.820
AHC14619.1
Hypothetical protein.
       0.773
AHC13953.1
Cold-shock DEAD-box protein A.
  
 0.734
AHC15397.1
ATP-dependent RNA helicase RhlE; Belongs to the DEAD box helicase family.
  
 0.734
AHC15840.1
Cold-shock DEAD-box protein A; Belongs to the DEAD box helicase family.
  
 0.734
AHC16172.1
Hypothetical protein.
  
 0.734
AHC14634.1
ATPase YjeE, predicted to have essential role in cell wall biosynthesis.
  
 
 0.733
AHC16557.1
Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  
   0.688
Your Current Organism:
Salinispira pacifica
NCBI taxonomy Id: 1307761
Other names: DSM 27196, JCM 18663, S. pacifica, Salinispira pacifica Ben Hania et al. 2015, Spirochaeta sp. L21-RPul-D2, strain L21-RPul-D2
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