Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AHC15616.1Sensor histidine kinase/response regulator. (1036 aa)    
Predicted Functional Partners:
AHC15332.1
Hypothetical protein.
 
 
0.967
AHC15617.1
Response regulatory protein.
 
 
0.964
AHC13471.1
Serine phosphatase RsbU, regulator of sigma subunit.
 
 
 0.944
AHC14163.1
GGDEF domain protein.
 
 
 0.942
AHC15521.1
Hypothetical protein.
 
 
 0.940
AHC16050.1
Hypothetical protein.
 
 
0.938
AHC14948.1
Two-component hybrid sensor and regulator.
 
 
 0.936
AHC14706.1
Hypothetical protein.
 
 
0.935
AHC15910.1
Chemotaxis protein methyltransferase CheR.
 
 
0.933
AHC14969.1
Ammonium transporter.
 
 
 0.927
Your Current Organism:
Salinispira pacifica
NCBI taxonomy Id: 1307761
Other names: DSM 27196, JCM 18663, S. pacifica, Salinispira pacifica Ben Hania et al. 2015, Spirochaeta sp. L21-RPul-D2, strain L21-RPul-D2
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