AHC15958.1 protein (Salinispira pacifica) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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gene co-occurrence

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protein homology

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Score

AHC15958.1

Adenylate cyclase. (122 aa)

Predicted Functional Partners:

AHC15957.1

0.908

AHC15959.1

0.826

AHC15910.1

0.824

AHC16166.1

0.776

AHC14706.1

0.774

AHC14969.1

0.757

AHC14341.1

0.733

AHC16607.1

0.730

AHC13900.1

0.729

AHC15332.1

0.724

Your Current Organism:

Salinispira pacifica

NCBI taxonomy Id: 1307761
Other names: DSM 27196, JCM 18663, S. pacifica, Salinispira pacifica Ben Hania et al. 2015, Spirochaeta sp. L21-RPul-D2, strain L21-RPul-D2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHC13900.1	AHC14341.1	L21SP2_0468	L21SP2_0921	Phosphate regulon transcriptional regulatory protein PhoB (SphR).	Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY.	0.599
AHC13900.1	AHC14706.1	L21SP2_0468	L21SP2_1307	Phosphate regulon transcriptional regulatory protein PhoB (SphR).	Hypothetical protein.	0.946
AHC13900.1	AHC14969.1	L21SP2_0468	L21SP2_1580	Phosphate regulon transcriptional regulatory protein PhoB (SphR).	Ammonium transporter.	0.723
AHC13900.1	AHC15332.1	L21SP2_0468	L21SP2_1961	Phosphate regulon transcriptional regulatory protein PhoB (SphR).	Hypothetical protein.	0.859
AHC13900.1	AHC15910.1	L21SP2_0468	L21SP2_2558	Phosphate regulon transcriptional regulatory protein PhoB (SphR).	Chemotaxis protein methyltransferase CheR.	0.642
AHC13900.1	AHC15957.1	L21SP2_0468	L21SP2_2605	Phosphate regulon transcriptional regulatory protein PhoB (SphR).	Two-component sensor histidine kinase.	0.484
AHC13900.1	AHC15958.1	L21SP2_0468	L21SP2_2606	Phosphate regulon transcriptional regulatory protein PhoB (SphR).	Adenylate cyclase.	0.729
AHC13900.1	AHC16166.1	L21SP2_0468	L21SP2_2816	Phosphate regulon transcriptional regulatory protein PhoB (SphR).	Signal transduction histidine kinase.	0.501
AHC13900.1	AHC16607.1	L21SP2_0468	L21SP2_3267	Phosphate regulon transcriptional regulatory protein PhoB (SphR).	DNA-binding response regulator CtrA.	0.730
AHC14341.1	AHC13900.1	L21SP2_0921	L21SP2_0468	Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY.	Phosphate regulon transcriptional regulatory protein PhoB (SphR).	0.599
AHC14341.1	AHC14706.1	L21SP2_0921	L21SP2_1307	Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY.	Hypothetical protein.	0.461
AHC14341.1	AHC14969.1	L21SP2_0921	L21SP2_1580	Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY.	Ammonium transporter.	0.674
AHC14341.1	AHC15332.1	L21SP2_0921	L21SP2_1961	Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY.	Hypothetical protein.	0.581
AHC14341.1	AHC15910.1	L21SP2_0921	L21SP2_2558	Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY.	Chemotaxis protein methyltransferase CheR.	0.689
AHC14341.1	AHC15958.1	L21SP2_0921	L21SP2_2606	Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY.	Adenylate cyclase.	0.733
AHC14341.1	AHC16607.1	L21SP2_0921	L21SP2_3267	Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY.	DNA-binding response regulator CtrA.	0.562
AHC14706.1	AHC13900.1	L21SP2_1307	L21SP2_0468	Hypothetical protein.	Phosphate regulon transcriptional regulatory protein PhoB (SphR).	0.946
AHC14706.1	AHC14341.1	L21SP2_1307	L21SP2_0921	Hypothetical protein.	Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY.	0.461
AHC14706.1	AHC14969.1	L21SP2_1307	L21SP2_1580	Hypothetical protein.	Ammonium transporter.	0.907
AHC14706.1	AHC15332.1	L21SP2_1307	L21SP2_1961	Hypothetical protein.	Hypothetical protein.	0.991

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Network Stats

number of nodes:

5

number of edges:

10

average node degree:

4

avg. local clustering coefficient:

1

expected number of edges:

4

PPI enrichment p-value:

0.00543

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0007165

Signal transduction

7 of 83

1.39

1.75

3.73e-06

GO:0000160

Phosphorelay signal transduction system

6 of 75

1.36

1.55

2.55e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2251

PAS domain, and Nucleotide cyclase

9 of 17

2.18

6.3

1.30e-15

CL:2254

PAS-associated, C-terminal, and Nucleotide cyclase

6 of 10

2.24

4.69

9.94e-11

CL:2232

Signal transduction response regulator, receiver domain, and Histidine kinase-like ATPases

11 of 74

1.63

3.89

1.30e-15

CL:2257

PAC motif

4 of 5

2.36

3.3

3.60e-07

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02020

Two-component system

8 of 283

0.91

0.87

6.68e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0597

Phosphoprotein

10 of 61

1.68

3.89

3.62e-14

KW-0418

Kinase

7 of 101

1.3

1.67

1.33e-06

KW-0902

Two-component regulatory system

2 of 12

1.68

0.74

0.0345

KW-0067

ATP-binding

6 of 245

0.85

0.62

0.0053

KW-0238

DNA-binding

4 of 139

0.92

0.52

0.0345

(more ...)

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR001789

Signal transduction response regulator, receiver domain

10 of 52

1.74

4.15

5.38e-14

IPR011006

CheY-like superfamily

10 of 55

1.72

4.05

5.38e-14

IPR001610

PAC motif

5 of 6

2.38

4.0

1.17e-08

IPR036097

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily

7 of 26

1.89

3.65

9.43e-10

IPR003661

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain

7 of 27

1.87

3.61

9.43e-10

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00448

cheY-homologous receiver domain

10 of 52

1.74

4.34

4.32e-15

SM00388

His Kinase A (phosphoacceptor) domain

7 of 29

1.84

3.71

2.21e-10

SM00086

Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)

5 of 11

2.12

3.61

1.99e-08

SM00387

Histidine kinase-like ATPases

7 of 34

1.77

3.46

3.95e-10

SM00091

PAS domain

5 of 16

1.96

3.16

7.35e-08

(more ...)

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