Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AHC16218.1Citrate synthase (si); Belongs to the citrate synthase family. (381 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.993
AHC15540.1
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.980
AHC16678.1
Aconitate hydratase.
 
 0.975
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.961
AHC15896.1
Malate synthase.
   
 0.956
AHC16279.1
Pyruvate-flavodoxin oxidoreductase.
    
 0.948
AHC15347.1
3-ketoacyl-CoA thiolase, Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.945
AHC16154.1
Pyruvate carboxyl transferase subunit B.
  
 
 0.945
AHC16358.1
3-ketoacyl-CoA thiolase, Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.945
AHC16146.1
2-oxoglutarate oxidoreductase, alpha subunit.
    
 0.929
Your Current Organism:
Salinispira pacifica
NCBI taxonomy Id: 1307761
Other names: DSM 27196, JCM 18663, S. pacifica, Salinispira pacifica Ben Hania et al. 2015, Spirochaeta sp. L21-RPul-D2, strain L21-RPul-D2
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.