Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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sucCSuccinyl-CoA ligase [ADP-forming] beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (375 aa)    
Predicted Functional Partners:
sucD
Succinyl-CoA ligase [ADP-forming] alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.999
AHC16225.1
Succinate dehydrogenase flavoprotein subunit.
 
 0.996
AHC16224.1
Succinate dehydrogenase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
 
 0.995
AHC16220.1
Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.991
AHC16221.1
2-oxoglutarate dehydrogenase E1 component.
 
 0.989
AHC15540.1
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.971
AHC16146.1
2-oxoglutarate oxidoreductase, alpha subunit.
    
 0.947
AHC16218.1
Citrate synthase (si); Belongs to the citrate synthase family.
  
 0.929
AHC15895.1
Isocitrate lyase, group III, Mycobacterial type ICL2.
   
 
 0.925
AHC16147.1
2-oxoglutarate oxidoreductase, beta subunit.
    
 0.920
Your Current Organism:
Salinispira pacifica
NCBI taxonomy Id: 1307761
Other names: DSM 27196, JCM 18663, S. pacifica, Salinispira pacifica Ben Hania et al. 2015, Spirochaeta sp. L21-RPul-D2, strain L21-RPul-D2
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