Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AHC16244.1L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (559 aa)    
Predicted Functional Partners:
fni
Hydroxymethylglutaryl-CoA reductase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). Belongs to the IPP isomerase type 2 family.
  
  
 0.853
AHC16245.1
D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
  
 0.682
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
  
 0.608
AHC14912.1
Sodium/pantothenate symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
   
 0.577
AHC15655.1
Proline dehydrogenase(Proline oxidase) / Delta-1-pyrroline-5-carboxylate dehydrogenase.
  
  
 0.482
AHC16279.1
Pyruvate-flavodoxin oxidoreductase.
     
 0.470
AHC16243.1
Integral membrane protein.
       0.465
AHC15067.1
Hypothetical protein.
  
     0.432
AHC15337.1
Aspartate ammonia-lyase.
  
  
 0.420
AHC15730.1
Multifunctional fatty acid oxidation complex subunit alpha.
   
  
 0.418
Your Current Organism:
Salinispira pacifica
NCBI taxonomy Id: 1307761
Other names: DSM 27196, JCM 18663, S. pacifica, Salinispira pacifica Ben Hania et al. 2015, Spirochaeta sp. L21-RPul-D2, strain L21-RPul-D2
Server load: low (24%) [HD]