Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pyrEOrotidine 5'-phosphate decarboxylase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP); Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily. (483 aa)    
Predicted Functional Partners:
AHC14805.1
Aspartate carbamoyltransferase/ Aspartate carbamoyltransferase regulatory chain (PyrI).
 
  
 0.999
AHC15055.1
Putative dihydropyrimidine dehydrogenase [NADP+], similar to dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate.
  
 0.998
AHC15623.1
Dihydroorotate dehydrogenase electron transfer subunit.
  
 
 0.998
pyrD
Dihydroorotate dehydrogenase, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.
 
 0.998
AHC16332.1
Putative dihydropyrimidine dehydrogenase [NADP+], similar to dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate.
  
 0.998
carA
Carbamoyl-phosphate synthase small chain; Belongs to the CarA family.
 
  
 0.996
AHC16699.1
Uracil permease.
  
  
 0.988
AHC16350.1
Oxidoreductase, NAD-binding protein.
  
  
 0.986
AHC14537.1
Uracil phosphoribosyltransferase.
  
 0.960
AHC14792.1
Uridine kinase.
  
 0.956
Your Current Organism:
Salinispira pacifica
NCBI taxonomy Id: 1307761
Other names: DSM 27196, JCM 18663, S. pacifica, Salinispira pacifica Ben Hania et al. 2015, Spirochaeta sp. L21-RPul-D2, strain L21-RPul-D2
Server load: medium (48%) [HD]