Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AHC16311.1Phosphomevalonate kinase. (254 aa)    
Predicted Functional Partners:
AHC16308.1
Diphosphomevalonate decarboxylase.
    
 0.985
AHC16312.1
Mevalonate kinase.
    
 0.969
AHC16309.1
Hypothetical protein.
       0.773
AHC16310.1
Hypothetical protein.
       0.773
fni
Hydroxymethylglutaryl-CoA reductase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). Belongs to the IPP isomerase type 2 family.
     
 0.655
AHC16307.1
Diphosphomevalonate decarboxylase.
     
 0.580
AHC16305.1
Hydroxymethylglutaryl-CoA synthase.
       0.552
Your Current Organism:
Salinispira pacifica
NCBI taxonomy Id: 1307761
Other names: DSM 27196, JCM 18663, S. pacifica, Salinispira pacifica Ben Hania et al. 2015, Spirochaeta sp. L21-RPul-D2, strain L21-RPul-D2
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