Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AHC16634.1Phosphotransferase system, phosphocarrier protein HPr. (88 aa)    
Predicted Functional Partners:
AHC14742.1
Phosphoenolpyruvate-protein phosphotransferase of PTS system; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.998
AHC15472.1
Phosphoenolpyruvate-protein phosphotransferase of PTS system; Belongs to the PEP-utilizing enzyme family.
 
 
 0.969
hprK
HPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
 
 
 
 0.957
AHC15367.1
PTS system, fructose-specific IIABC component.
 
 
 0.933
AHC15536.1
Phosphotransferase system, phosphocarrier protein HPr.
  
  
0.914
AHC16746.1
PTS system, fructose-specific IIABC component.
 
  
 0.744
AHC16747.1
PTS system, fructose-specific IIA/ IIB/ IIC component.
 
  
 0.740
AHC13544.1
PTS system, fructose-specific IIABC component.
 
  
 0.739
AHC14285.1
PTS system, fructose-specific component IIA/ IIB/ IIC.
  
  
 0.717
pfkA
Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, alpha subunit; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
  
  
 0.678
Your Current Organism:
Salinispira pacifica
NCBI taxonomy Id: 1307761
Other names: DSM 27196, JCM 18663, S. pacifica, Salinispira pacifica Ben Hania et al. 2015, Spirochaeta sp. L21-RPul-D2, strain L21-RPul-D2
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