node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKJ64014.1 | coaD | L21SP4_00746 | L21SP4_02345 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate-cysteine ligase. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.927 |
AKJ64014.1 | ribF | L21SP4_00746 | L21SP4_00065 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate-cysteine ligase. | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 0.567 |
AKJ64881.1 | ribF | L21SP4_01638 | L21SP4_00065 | Beta-lactamase domain protein. | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 0.593 |
coaD | AKJ64014.1 | L21SP4_02345 | L21SP4_00746 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate-cysteine ligase. | 0.927 |
coaD | ribF | L21SP4_02345 | L21SP4_00065 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 0.691 |
infB | nusA | L21SP4_00062 | L21SP4_00061 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Putative transcription termination/antitermination protein NusA; Participates in both transcription termination and antitermination. | 0.976 |
infB | rbfA | L21SP4_00062 | L21SP4_00063 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | 0.890 |
infB | ribF | L21SP4_00062 | L21SP4_00065 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 0.681 |
infB | truB | L21SP4_00062 | L21SP4_00064 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.985 |
murJ | ribF | L21SP4_00849 | L21SP4_00065 | Putative peptidoglycan biosynthesis protein MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 0.594 |
nusA | infB | L21SP4_00061 | L21SP4_00062 | Putative transcription termination/antitermination protein NusA; Participates in both transcription termination and antitermination. | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.976 |
nusA | rbfA | L21SP4_00061 | L21SP4_00063 | Putative transcription termination/antitermination protein NusA; Participates in both transcription termination and antitermination. | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | 0.776 |
nusA | ribF | L21SP4_00061 | L21SP4_00065 | Putative transcription termination/antitermination protein NusA; Participates in both transcription termination and antitermination. | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 0.741 |
nusA | ribH | L21SP4_00061 | L21SP4_01781 | Putative transcription termination/antitermination protein NusA; Participates in both transcription termination and antitermination. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.865 |
nusA | truB | L21SP4_00061 | L21SP4_00064 | Putative transcription termination/antitermination protein NusA; Participates in both transcription termination and antitermination. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.930 |
rbfA | infB | L21SP4_00063 | L21SP4_00062 | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.890 |
rbfA | nusA | L21SP4_00063 | L21SP4_00061 | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | Putative transcription termination/antitermination protein NusA; Participates in both transcription termination and antitermination. | 0.776 |
rbfA | ribF | L21SP4_00063 | L21SP4_00065 | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 0.840 |
rbfA | truB | L21SP4_00063 | L21SP4_00064 | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.946 |
ribE | ribF | L21SP4_01778 | L21SP4_00065 | Riboflavin synthase. | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 0.926 |