STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
frdAFumarate reductase flavoprotein subunit. (646 aa)    
Predicted Functional Partners:
frdB
Fumarate reductase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
 
 0.999
ALO15453.1
Succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family.
 
 
 0.998
hndC_1
NADP-reducing hydrogenase subunit HndC.
  
 
 0.996
nifJ
Pyruvate-flavodoxin oxidoreductase.
  
 
 0.993
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
 
 0.979
sucC
Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.978
sucD
Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.976
sad
Succinate semialdehyde dehydrogenase [NAD(P)+] Sad.
  
 0.933
nqo4
NADH-quinone oxidoreductase subunit 4; Belongs to the complex I 49 kDa subunit family.
  
 
 0.928
sucA
2-oxoglutarate dehydrogenase E1 component.
 
 0.919
Your Current Organism:
Salinivirga cyanobacteriivorans
NCBI taxonomy Id: 1307839
Other names: DSM 27204, JCM 31231, KCTC 15528, S. cyanobacteriivorans, Salinivirga cyanobacteriivorans Ben Hania et al. 2017, bacterium L21-Spi-D4, strain L21-Spi-D4
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