STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
guaAGMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. (532 aa)    
Predicted Functional Partners:
argS
arginyl-tRNA synthetase.
  
  
 0.999
rplK
LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
  
    0.999
SDU79509.1
IMP dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
 0.999
SDU79520.1
IMP dehydrogenase.
 
 0.999
SDU79899.1
IMP dehydrogenase.
 0.999
SDU81263.1
Phosphoribosylformylglycinamidine synthase.
  
  
 0.999
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 0.998
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.994
pheT
phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.990
pyrD
Dihydroorotate dehydrogenase (NAD+) catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.
  
 0.983
Your Current Organism:
Arcanobacterium phocae
NCBI taxonomy Id: 131112
Other names: A. phocae, CIP 105740, DSM 10002, LMG 18722, LMG:18722, strain M1590/94/3
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