SDU79886.1 protein (Arcanobacterium phocae) - STRING interaction network

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second shell of interactors

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a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

SDU79886.1

Hypothetical protein. (381 aa)

Predicted Functional Partners:

SDU79880.1

0.948

SDU79885.1

0.940

SDU82471.1

0.774

SDU82482.1

0.768

SDU79068.1

0.737

SDU78322.1

0.718

SDU78279.1

0.673

SDU79509.1

0.671

SDU78717.1

0.651

SDU79529.1

0.651

Your Current Organism:

Arcanobacterium phocae

NCBI taxonomy Id: 131112
Other names: A. phocae, CIP 105740, DSM 10002, LMG 18722, LMG:18722, strain M1590/94/3

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDU78279.1	SDU79886.1	SAMN04489737_0405	SAMN04489737_1030	Nitrate/nitrite transporter NarK.	Hypothetical protein.	0.673
SDU78322.1	SDU78717.1	SAMN04489737_0426	SAMN04489737_0587	LPXTG-motif cell wall anchor domain-containing protein.	Cna protein B-type domain-containing protein.	0.700
SDU78322.1	SDU79068.1	SAMN04489737_0426	SAMN04489737_0726	LPXTG-motif cell wall anchor domain-containing protein.	LPXTG-motif cell wall anchor domain-containing protein.	0.700
SDU78322.1	SDU79529.1	SAMN04489737_0426	SAMN04489737_0908	LPXTG-motif cell wall anchor domain-containing protein.	Hypothetical protein.	0.700
SDU78322.1	SDU79886.1	SAMN04489737_0426	SAMN04489737_1030	LPXTG-motif cell wall anchor domain-containing protein.	Hypothetical protein.	0.718
SDU78322.1	SDU82471.1	SAMN04489737_0426	SAMN04489737_1740	LPXTG-motif cell wall anchor domain-containing protein.	Cna protein B-type domain-containing protein.	0.700
SDU78322.1	SDU82482.1	SAMN04489737_0426	SAMN04489737_1742	LPXTG-motif cell wall anchor domain-containing protein.	LPXTG-motif cell wall anchor domain-containing protein.	0.699
SDU78717.1	SDU78322.1	SAMN04489737_0587	SAMN04489737_0426	Cna protein B-type domain-containing protein.	LPXTG-motif cell wall anchor domain-containing protein.	0.700
SDU78717.1	SDU79886.1	SAMN04489737_0587	SAMN04489737_1030	Cna protein B-type domain-containing protein.	Hypothetical protein.	0.651
SDU78717.1	SDU82482.1	SAMN04489737_0587	SAMN04489737_1742	Cna protein B-type domain-containing protein.	LPXTG-motif cell wall anchor domain-containing protein.	0.651
SDU79068.1	SDU78322.1	SAMN04489737_0726	SAMN04489737_0426	LPXTG-motif cell wall anchor domain-containing protein.	LPXTG-motif cell wall anchor domain-containing protein.	0.700
SDU79068.1	SDU79886.1	SAMN04489737_0726	SAMN04489737_1030	LPXTG-motif cell wall anchor domain-containing protein.	Hypothetical protein.	0.737
SDU79068.1	SDU82482.1	SAMN04489737_0726	SAMN04489737_1742	LPXTG-motif cell wall anchor domain-containing protein.	LPXTG-motif cell wall anchor domain-containing protein.	0.651
SDU79509.1	SDU79886.1	SAMN04489737_0901	SAMN04489737_1030	IMP dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	Hypothetical protein.	0.671
SDU79509.1	SDU82482.1	SAMN04489737_0901	SAMN04489737_1742	IMP dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	LPXTG-motif cell wall anchor domain-containing protein.	0.671
SDU79529.1	SDU78322.1	SAMN04489737_0908	SAMN04489737_0426	Hypothetical protein.	LPXTG-motif cell wall anchor domain-containing protein.	0.700
SDU79529.1	SDU79886.1	SAMN04489737_0908	SAMN04489737_1030	Hypothetical protein.	Hypothetical protein.	0.651
SDU79529.1	SDU82482.1	SAMN04489737_0908	SAMN04489737_1742	Hypothetical protein.	LPXTG-motif cell wall anchor domain-containing protein.	0.651
SDU79880.1	SDU79885.1	SAMN04489737_1028	SAMN04489737_1029	Hypothetical protein.	Hypothetical protein.	0.975
SDU79880.1	SDU79886.1	SAMN04489737_1028	SAMN04489737_1030	Hypothetical protein.	Hypothetical protein.	0.948

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Network Stats

number of nodes:

4

number of edges:

3

average node degree:

1.5

avg. local clustering coefficient:

0.75

expected number of edges:

3

PPI enrichment p-value:

0.564

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0055071

Manganese ion homeostasis

2 of 3

3.57

2.33

0.0020

GO:0033212

Iron import into cell

2 of 5

3.35

2.3

0.0021

GO:0071578

Zinc ion import across plasma membrane

2 of 8

3.14

2.29

0.0021

GO:0006882

Cellular zinc ion homeostasis

2 of 23

2.68

1.84

0.0066

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0015086

Cadmium ion transmembrane transporter activity

2 of 6

3.27

2.38

0.0017

GO:0005384

Manganese ion transmembrane transporter activity

2 of 11

3.0

2.36

0.0017

GO:0005381

Iron ion transmembrane transporter activity

2 of 9

3.09

2.36

0.0017

GO:0015296

Anion:cation symporter activity

2 of 18

2.79

2.15

0.0028

GO:0005385

Zinc ion transmembrane transporter activity

2 of 26

2.63

1.96

0.0045

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:25082

Zinc ion transport

2 of 18

2.79

1.55

0.0151

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

tgu04216

Ferroptosis

2 of 28

2.6

2.32

0.0016

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-442380

Zinc influx into cells by the SLC39 gene family

2 of 17

2.81

1.87

0.0062

MAP-435354

Zinc transporters

2 of 25

2.65

1.84

0.0064

MAP-425410

Metal ion SLC transporters

2 of 38

2.46

1.68

0.0094

MAP-425366

Transport of bile salts and organic acids, metal ions and amine compounds

2 of 96

2.06

1.1

0.0429

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009925

Basal plasma membrane

2 of 44

2.4

1.21

0.0356

GOCC:0005765

Lysosomal membrane

2 of 69

2.21

1.19

0.0356

GOCC:0045177

Apical part of cell

2 of 97

2.06

1.16

0.0356

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