STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EG19_03775Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)    
Predicted Functional Partners:
EG19_05955
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.932
EG19_09985
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.881
topA
Hypothetical protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA sup [...]
   
 0.880
EG19_06080
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.799
EG19_00805
Hypothetical protein; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
  
  
 0.753
pyrB
Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
      0.661
EG19_01185
Single-stranded DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.625
EG19_11635
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0102 family.
 
    0.620
EG19_04980
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0758 family.
  
  
 0.592
EG19_03780
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.561
Your Current Organism:
Thermoanaerobaculum aquaticum
NCBI taxonomy Id: 1312852
Other names: DSM 24856, JCM 18256, T. aquaticum, Thermoanaerobaculum aquaticum Losey et al. 2013, bacterium MP-01, strain MP-01
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.