STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A0N4ZBT9Guanylate cyclase. (1123 aa)    
Predicted Functional Partners:
A0A0N4ZEY7
Uncharacterized protein.
     
 0.829
A0A0N4ZKF6
Uncharacterized protein.
     
 0.829
A0A0N4ZKB4
Diphthine--ammonia ligase; Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP.
    
  0.784
A0A0N5A559
Nucleoside diphosphate kinase.
    
 0.729
A0A0N5A184
Nudix hydrolase domain-containing protein.
     
 0.727
A0A0N4Z6J6
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
    
  0.723
A0A0N4Z9R8
Uncharacterized protein.
    
 0.656
A0A0N4ZIJ5
Uncharacterized protein.
    
 0.601
A0A0N5A3Y9
Guanylate cyclase.
  
  
 
0.585
A0A0N4ZF26
Phosphodiesterase.
  
 
 0.524
Your Current Organism:
Parastrongyloides trichosuri
NCBI taxonomy Id: 131310
Other names: P. trichosuri
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.