STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A0N4ZER5Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family. (535 aa)    
Predicted Functional Partners:
A0A0N4ZFB9
AAA_23 domain-containing protein.
  
 0.998
A0A0N4ZRY0
AAA_23 domain-containing protein.
  
 0.998
A0A0N4Z7U7
Uncharacterized protein.
   
 0.994
A0A0N4ZG78
Uncharacterized protein.
  
 0.992
A0A0N4ZPL3
Ku domain-containing protein.
   
 0.990
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 0.987
A0A0N4ZJ79
Uncharacterized protein.
   
 0.985
A0A0N5A2L6
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 0.985
A0A0N4ZN87
MADF domain-containing protein.
   
 0.975
A0A0N4ZSS9
GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly.
    
  0.970
Your Current Organism:
Parastrongyloides trichosuri
NCBI taxonomy Id: 131310
Other names: P. trichosuri
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.