node1 | node2 | node1 annotation | node2 annotation | score |
A0A0N4Z276 | A0A0N4Z8S3 | NifU_N domain-containing protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Fe-S_biosyn domain-containing protein. | 0.985 |
A0A0N4Z276 | A0A0N4ZFT3 | NifU_N domain-containing protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | MOSC domain-containing protein. | 0.999 |
A0A0N4Z276 | A0A0N4ZG56 | NifU_N domain-containing protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | 2Fe-2S ferredoxin-type domain-containing protein. | 0.945 |
A0A0N4Z276 | A0A0N4ZP91 | NifU_N domain-containing protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Adenylyltransferase and sulfurtransferase MOCS3 homolog; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of the sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards U [...] | 0.576 |
A0A0N4Z276 | A0A0N4ZQX2 | NifU_N domain-containing protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | J domain-containing protein. | 0.998 |
A0A0N4Z276 | A0A0N4ZS81 | NifU_N domain-containing protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Nfu_N domain-containing protein. | 0.888 |
A0A0N4Z276 | A0A0N4ZVA4 | NifU_N domain-containing protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Aminotran_5 domain-containing protein. | 0.999 |
A0A0N4Z276 | A0A0N5A2H7 | NifU_N domain-containing protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Uncharacterized protein; Belongs to the complex I LYR family. | 0.989 |
A0A0N4Z276 | A0A0N5A7C6 | NifU_N domain-containing protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | 2Fe-2S ferredoxin-type domain-containing protein. | 0.945 |
A0A0N4Z8S3 | A0A0N4Z276 | Fe-S_biosyn domain-containing protein. | NifU_N domain-containing protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | 0.985 |
A0A0N4Z8S3 | A0A0N4ZFT3 | Fe-S_biosyn domain-containing protein. | MOSC domain-containing protein. | 0.859 |
A0A0N4Z8S3 | A0A0N4ZG56 | Fe-S_biosyn domain-containing protein. | 2Fe-2S ferredoxin-type domain-containing protein. | 0.793 |
A0A0N4Z8S3 | A0A0N4ZP91 | Fe-S_biosyn domain-containing protein. | Adenylyltransferase and sulfurtransferase MOCS3 homolog; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of the sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards U [...] | 0.613 |
A0A0N4Z8S3 | A0A0N4ZQX2 | Fe-S_biosyn domain-containing protein. | J domain-containing protein. | 0.974 |
A0A0N4Z8S3 | A0A0N4ZS81 | Fe-S_biosyn domain-containing protein. | Nfu_N domain-containing protein. | 0.934 |
A0A0N4Z8S3 | A0A0N4ZVA4 | Fe-S_biosyn domain-containing protein. | Aminotran_5 domain-containing protein. | 0.922 |
A0A0N4Z8S3 | A0A0N5A2H7 | Fe-S_biosyn domain-containing protein. | Uncharacterized protein; Belongs to the complex I LYR family. | 0.621 |
A0A0N4Z8S3 | A0A0N5A7C6 | Fe-S_biosyn domain-containing protein. | 2Fe-2S ferredoxin-type domain-containing protein. | 0.767 |
A0A0N4ZFT3 | A0A0N4Z276 | MOSC domain-containing protein. | NifU_N domain-containing protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | 0.999 |
A0A0N4ZFT3 | A0A0N4Z8S3 | MOSC domain-containing protein. | Fe-S_biosyn domain-containing protein. | 0.859 |