STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A0N4ZZR7Histidine kinase domain-containing protein. (1881 aa)    
Predicted Functional Partners:
A0A0N4ZG12
ENDO3c domain-containing protein.
  
 
 0.906
A0A0N4ZER5
Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family.
  
  
 0.704
A0A0N4ZVN2
RF_PROK_I domain-containing protein.
     
 0.677
A0A0N4ZMM9
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
   
 
 0.670
A0A0N4ZKF0
Uncharacterized protein.
  
  
 0.665
NTH1
Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.
     
 0.663
A0A0N5A2M6
DNA_mis_repair domain-containing protein.
   
 
 0.654
A0A0N4ZL78
Alkyl transferase; Belongs to the UPP synthase family.
     
 0.611
A0A0N4ZG78
Uncharacterized protein.
   
 
 0.609
A0A0N4ZX70
Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
     
 0.603
Your Current Organism:
Parastrongyloides trichosuri
NCBI taxonomy Id: 131310
Other names: P. trichosuri
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.