STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A0N5A1F3Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. (324 aa)    
Predicted Functional Partners:
A0A0N4ZFX4
Eukaryotic translation initiation factor 5A.
  
 0.984
A0A0N4ZI09
Uncharacterized protein.
   
 0.954
A0A0N4ZQT3
Triosephosphate isomerase.
     
 0.868
A0A0N4Z8S3
Fe-S_biosyn domain-containing protein.
   
 
 0.856
A0A0N4ZY03
Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
     
 0.837
A0A0N4Z193
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
   
 
 0.836
A0A0N5A567
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.833
A0A0N4Z9U1
Malate synthase; Belongs to the malate synthase family.
    
  0.832
A0A0N4ZJA9
WD_REPEATS_REGION domain-containing protein.
   
    0.828
A0A0N5A744
Uncharacterized protein.
    
  0.828
Your Current Organism:
Parastrongyloides trichosuri
NCBI taxonomy Id: 131310
Other names: P. trichosuri
Server load: low (22%) [HD]