STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysScysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (479 aa)    
Predicted Functional Partners:
CALK_1973
Serine O-acetyltransferase.
 
 
 0.995
CALK_2036
Cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.940
CALK_0073
Cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.936
CALK_2279
Cysteine synthase A.
  
 0.931
hisS
histidyl-tRNA synthetase.
  
  
 0.805
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
       0.782
CALK_0037
B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.746
glyA
Serine-glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.725
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 
  
 0.717
leuS
leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.702
Your Current Organism:
Chitinivibrio alkaliphilus
NCBI taxonomy Id: 1313304
Other names: C. alkaliphilus ACht1, Chitinivibrio alkaliphilus ACht1, candidate division TG3 bacterium ACht1, haloalkaliphilic bacterium ACht1
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