node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CALK_0037 | CALK_0470 | CALK_0037 | CALK_0470 | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | malonyl-CoA O-methyltransferase. | 0.743 |
CALK_0037 | CALK_1047 | CALK_0037 | CALK_1047 | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | GMP synthase. | 0.579 |
CALK_0037 | CALK_1811 | CALK_0037 | CALK_1811 | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pyridine nucleotide-disulfide oxidoreductase family protein; Belongs to the sulfur carrier protein TusA family. | 0.868 |
CALK_0037 | CALK_2461 | CALK_0037 | CALK_2461 | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Hypothetical protein. | 0.456 |
CALK_0037 | glyA | CALK_0037 | CALK_2248 | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Serine-glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.836 |
CALK_0469 | CALK_0470 | CALK_0469 | CALK_0470 | 8-amino-7-oxononanoate synthase. | malonyl-CoA O-methyltransferase. | 0.977 |
CALK_0469 | CALK_1047 | CALK_0469 | CALK_1047 | 8-amino-7-oxononanoate synthase. | GMP synthase. | 0.481 |
CALK_0469 | CALK_1811 | CALK_0469 | CALK_1811 | 8-amino-7-oxononanoate synthase. | Pyridine nucleotide-disulfide oxidoreductase family protein; Belongs to the sulfur carrier protein TusA family. | 0.713 |
CALK_0469 | CALK_2461 | CALK_0469 | CALK_2461 | 8-amino-7-oxononanoate synthase. | Hypothetical protein. | 0.487 |
CALK_0469 | glyA | CALK_0469 | CALK_2248 | 8-amino-7-oxononanoate synthase. | Serine-glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.731 |
CALK_0470 | CALK_0037 | CALK_0470 | CALK_0037 | malonyl-CoA O-methyltransferase. | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.743 |
CALK_0470 | CALK_0469 | CALK_0470 | CALK_0469 | malonyl-CoA O-methyltransferase. | 8-amino-7-oxononanoate synthase. | 0.977 |
CALK_0470 | CALK_1047 | CALK_0470 | CALK_1047 | malonyl-CoA O-methyltransferase. | GMP synthase. | 0.757 |
CALK_0470 | CALK_1811 | CALK_0470 | CALK_1811 | malonyl-CoA O-methyltransferase. | Pyridine nucleotide-disulfide oxidoreductase family protein; Belongs to the sulfur carrier protein TusA family. | 0.903 |
CALK_0470 | CALK_2461 | CALK_0470 | CALK_2461 | malonyl-CoA O-methyltransferase. | Hypothetical protein. | 0.469 |
CALK_0470 | glyA | CALK_0470 | CALK_2248 | malonyl-CoA O-methyltransferase. | Serine-glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.716 |
CALK_0743 | CALK_2461 | CALK_0743 | CALK_2461 | Hypothetical protein. | Hypothetical protein. | 0.452 |
CALK_1047 | CALK_0037 | CALK_1047 | CALK_0037 | GMP synthase. | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.579 |
CALK_1047 | CALK_0469 | CALK_1047 | CALK_0469 | GMP synthase. | 8-amino-7-oxononanoate synthase. | 0.481 |
CALK_1047 | CALK_0470 | CALK_1047 | CALK_0470 | GMP synthase. | malonyl-CoA O-methyltransferase. | 0.757 |