STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CALK_2499Integron integrase; Belongs to the 'phage' integrase family. (396 aa)    
Predicted Functional Partners:
CALK_0639
Pyruvate:feredoxin oxidoreductase.
  
 
  0.699
CALK_1343
Amidophosphoribosyl-transferase.
   
    0.603
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.587
CALK_1670
Prephenate dehydrogenase.
  
    0.572
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.466
polA
DNA polymerase type I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.454
CALK_1047
GMP synthase.
     
 0.436
CALK_1221
Malic enzyme; Belongs to the malic enzymes family.
   
 0.428
CALK_2497
Hypothetical protein.
       0.423
CALK_2456
Phosphate acetyltransferase.
    
 0.419
Your Current Organism:
Chitinivibrio alkaliphilus
NCBI taxonomy Id: 1313304
Other names: C. alkaliphilus ACht1, Chitinivibrio alkaliphilus ACht1, candidate division TG3 bacterium ACht1, haloalkaliphilic bacterium ACht1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.